Rebound effect: See somogyi effect.
Regular insulin: A type of insulin that is rapid-acting.
Renal: Relating to the kidneys.
Retina: The center part of the back lining of the eye that senses light. It has many small blood vessels that are sometimes harmed when a person has had diabetes for a long time.
Retinopathy: A disease of the small blood vessels in the retina of the eye.
Risk factor: Anything that increases the chance of a person developing a disease or condition.
A key mechanism that appears to contribute to blood vessel damage in people with diabetes has been identified by researchers at Washington University School of Medicine in St. Louis.
Each year in the U.S. diabetes results in the amputation of about 65,700 legs or feet. About 85% of those began with a diabetic foot ulcer. And for Dr. David Schwegman, the mission to educate people about the issue is personal.
His father, a diabetic, had a foot ulcer that resulted in the amputation of his left leg, which contributed to his death, his son said.
"He became a statistic," Schwegman said. "He was one of the 50% of people that died within five years after having an amputation."